Target name

Q8JZL2: Melanin-concentrating hormone receptor 1


  Protein function

Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.

  Database links

Uniprot primary ID Q8JZL2
GRCP SARfari Variant Name mGPR24_1114
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 280
PharmGKB ID
KEGG ID mmu:207911
Entrez Gene (Gene ID) 207911
BindingDB Q8JZL2

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.93 0.85 0.89 0.89 0.95 0.78 Download
FP4 fingerprints 0.890 0.850 0.870 0.870 0.940 0.740 Download
MACCS fingerprints 0.890 0.850 0.870 0.870 0.950 0.740 Download
Daylight fingerprints 0.910 0.850 0.880 0.880 0.900 0.760 Download
ECFP2 fingerprints 0.960 0.790 0.880 0.880 0.950 0.760 Download
ECFP4 fingerprints 0.960 0.890 0.930 0.930 0.970 0.860 Download
ECFP6 fingerprints 0.950 0.940 0.950 0.950 0.970 0.890 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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