Target name

Q95136: D(1A) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID Q95136
GRCP SARfari Variant Name bDRD1_1293
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID bta:281125
Entrez Gene (Gene ID) 281125
BindingDB Q95136

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.84 0.64 0.74 0.77 0.77 0.49 Download
FP4 fingerprints 0.720 0.550 0.640 0.670 0.700 0.270 Download
MACCS fingerprints 0.780 0.590 0.680 0.710 0.730 0.370 Download
Daylight fingerprints 0.660 0.640 0.650 0.650 0.730 0.300 Download
ECFP2 fingerprints 0.690 0.590 0.640 0.660 0.710 0.280 Download
ECFP4 fingerprints 0.860 0.660 0.760 0.780 0.840 0.530 Download
ECFP6 fingerprints 0.860 0.680 0.770 0.790 0.880 0.550 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn