Target name

Q969V1: Melanin-concentrating hormone receptor 2


  Protein function

Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.

  Database links

Uniprot primary ID Q969V1
GRCP SARfari Variant Name hMCHR2_28
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 281
PharmGKB ID PA134950856
KEGG ID hsa:84539
Entrez Gene (Gene ID) 84539
BindingDB Q969V1

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.85 0.85 0.85 0.85 0.94 0.7 Download
FP4 fingerprints 0.770 0.810 0.790 0.790 0.890 0.580 Download
MACCS fingerprints 0.810 0.850 0.830 0.820 0.920 0.660 Download
Daylight fingerprints 0.770 0.960 0.870 0.850 0.940 0.750 Download
ECFP2 fingerprints 0.830 0.900 0.860 0.860 0.940 0.730 Download
ECFP4 fingerprints 0.870 0.910 0.890 0.890 0.970 0.780 Download
ECFP6 fingerprints 0.840 0.930 0.880 0.880 0.970 0.770 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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