Target name

Q99705: Melanin-concentrating hormone receptor 1


  Protein function

Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.

  Database links

Uniprot primary ID Q99705
GRCP SARfari Variant Name hGPR24_245
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 280
PharmGKB ID PA28867
KEGG ID hsa:2847
Entrez Gene (Gene ID) 2847
BindingDB Q99705

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.9 0.83 0.87 0.87 0.93 0.74 Download
FP4 fingerprints 0.840 0.770 0.810 0.810 0.890 0.610 Download
MACCS fingerprints 0.820 0.710 0.770 0.780 0.840 0.530 Download
Daylight fingerprints 0.800 0.860 0.830 0.830 0.900 0.660 Download
ECFP2 fingerprints 0.900 0.880 0.890 0.890 0.950 0.780 Download
ECFP4 fingerprints 0.920 0.930 0.920 0.920 0.970 0.850 Download
ECFP6 fingerprints 0.900 0.940 0.920 0.920 0.970 0.840 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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