Target name

Q9QZN9: Cannabinoid receptor 2


  Protein function

Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis (By similarity).

  Database links

Uniprot primary ID Q9QZN9
GRCP SARfari Variant Name rCB2R_1208
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 57
PharmGKB ID
KEGG ID rno:57302
Entrez Gene (Gene ID) 57302
BindingDB Q9QZN9

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.91 0.88 0.9 0.9 0.95 0.79 Download
FP4 fingerprints 0.770 0.800 0.780 0.780 0.860 0.570 Download
MACCS fingerprints 0.630 0.800 0.720 0.690 0.840 0.440 Download
Daylight fingerprints 0.870 0.900 0.880 0.880 0.920 0.770 Download
ECFP2 fingerprints 0.880 0.830 0.850 0.860 0.920 0.710 Download
ECFP4 fingerprints 0.930 0.900 0.910 0.920 0.970 0.830 Download
ECFP6 fingerprints 0.930 0.920 0.930 0.930 0.970 0.850 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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