Target name

Q9UBY5: Lysophosphatidic acid receptor 3


  Protein function

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.

  Database links

Uniprot primary ID Q9UBY5
GRCP SARfari Variant Name hEDG7_35
PDB ID
DrugBank ID
BioGrid ID 117108
GuidetoPHARMACOLOGY ID 274
PharmGKB ID PA162394213
KEGG ID hsa:23566
Entrez Gene (Gene ID) 23566
BindingDB Q9UBY5

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.91 0.73 0.82 0.84 0.84 0.66 Download
FP4 fingerprints 0.930 0.710 0.820 0.840 0.800 0.660 Download
MACCS fingerprints 0.910 0.730 0.820 0.840 0.810 0.660 Download
Daylight fingerprints 0.830 0.640 0.730 0.760 0.780 0.480 Download
ECFP2 fingerprints 0.910 0.730 0.820 0.840 0.740 0.660 Download
ECFP4 fingerprints 0.910 0.730 0.820 0.840 0.830 0.660 Download
ECFP6 fingerprints 0.910 0.730 0.820 0.840 0.840 0.660 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2015 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn