Target name

Q9UKP6: Urotensin-2 receptor


  Protein function

High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID Q9UKP6
GRCP SARfari Variant Name hGPR14_283
PDB ID
DrugBank ID
BioGrid ID 109097
GuidetoPHARMACOLOGY ID 365
PharmGKB ID PA28857
KEGG ID hsa:2837
Entrez Gene (Gene ID) 2837
BindingDB Q9UKP6

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.77 0.75 0.76 0.77 0.88 0.53 Download
FP4 fingerprints 0.740 0.720 0.730 0.730 0.820 0.460 Download
MACCS fingerprints 0.740 0.720 0.730 0.730 0.810 0.460 Download
Daylight fingerprints 0.700 0.850 0.770 0.750 0.820 0.550 Download
ECFP2 fingerprints 0.730 0.820 0.770 0.760 0.890 0.550 Download
ECFP4 fingerprints 0.820 0.940 0.880 0.870 0.940 0.760 Download
ECFP6 fingerprints 0.800 0.960 0.880 0.870 0.940 0.770 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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