Target name

Q9Y5Y4: Prostaglandin D2 receptor 2


  Protein function

Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca

  Database links

Uniprot primary ID Q9Y5Y4
GRCP SARfari Variant Name hGPR44_293
PDB ID
DrugBank ID DB00328 DB00605
BioGrid ID 116412
GuidetoPHARMACOLOGY ID 339
PharmGKB ID PA28891
KEGG ID hsa:11251
Entrez Gene (Gene ID) 11251
BindingDB Q9Y5Y4

  Model Performance Metrics

Fingerprint type Sensitivity Specificity Accuracy F1-score AUC Matthews_corrcoef Download model
FP2 fingerprints 0.79 0.81 0.8 0.79 0.88 0.59 Download
FP4 fingerprints 0.880 0.770 0.820 0.830 0.890 0.640 Download
MACCS fingerprints 0.820 0.780 0.800 0.800 0.870 0.600 Download
Daylight fingerprints 0.710 0.700 0.710 0.710 0.750 0.410 Download
ECFP2 fingerprints 0.960 0.790 0.870 0.880 0.910 0.750 Download
ECFP4 fingerprints 0.970 0.820 0.890 0.900 0.940 0.790 Download
ECFP6 fingerprints 0.940 0.830 0.880 0.890 0.930 0.770 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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